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  • Models And Experimental Results On Stimulation And Injury
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Kybernetische Aspekte der Strahlenschädigung

Cybernetic aspects of radiation damage

Helgoländer wissenschaftliche Meeresuntersuchungen volume 14, pages 195–212 (1966)Cite this article

Abstract

Starting with experimentally established radiobiological facts concerning cellular effects of ionizing radiation, the differences between single cells and tissues are discussed. A new classification for “size”-controlled tissues is proposed, and the relevant mathematical formulations are outlined. It is suggested that the different sensitivities of tissues against ionizing radiation may be explained on the basis of differently operating control mechanisms. As examples, root meristems, intestinal epithelium and blood forming organs are described in more detail.

Zusammenfassung

  1. 1.

    Ausgehend von grundlegenden experimentellen Fakten der Strahlenbiologie werden die Unterschiede zwischen Einzelzellen und Geweben behandelt, wobei vor allem auf Regelungsvorgänge, die auf die Konstanthaltung der Zellzahl hinwirken, eingegangen wird.

  2. 2.

    Es wird ein allgemeines Schema für Einteilung von Zellpopulationen vorgeschlagen, zu welchem als Klassifizierungsmerkmal die Art und Weise homöostatischer Regelungen der Zellzahl herangezogen wird. Die Einwirkung ionisierender Strahlung auf diese Modellsysteme wird diskutiert.

  3. 3.

    Mit Hilfe verschiedener Annahmen wird versucht, die unterschiedliche Strahlenempfindlichkeit verschiedener Organe zu deuten.

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  1. Institut für Biophysik, Strahlenzentrum der Justus Liebig-Universität, Gießen

    Jürgen Kiefer

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Kiefer, J. Kybernetische Aspekte der Strahlenschädigung. Helgolander Wiss. Meeresunters 14, 195–212 (1966). https://doi.org/10.1007/BF01611620

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