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Antibakterielle Inhaltsstoffe in Algen
1. Mitteilung
Antibacterial components in algae
1. Contribution
Helgoländer wissenschaftliche Meeresuntersuchungen volume 19, pages 376–384 (1969)
Abstract
Antibiotic components and intensity activities have been determined in several seaweed species. In order to obtain suitable preparations revealing antibacterial activities, several methods have been tested with respect to stability and desiccating the material. Antibiotic properties have been determined in preparations of 9 Chlorophyceae, 16 Rhodophyceae, and 16 Phaeophyceae using as criterion populations growth of 4 gram-positive and 2 gram-negative bacteria strains. The most potent antibiotic properties occur in Chlorophyceae. Among the Rhodophyceae tested, onlyChondrus crispus, Laurencia pinnatifida, Delesseria sanguinea, and — to a lesser degree —Rhodomela confervoides show considerable antibiotic activities. Among the Phaeophyceae, antibacterial potentials occur inHalidrys siliquosa, Fucus, Laminaria digitata, andDesmarestia viridis. The antibiotic compounds of Rhodophyceae and Chlorophyceae are mainly hydrophilic, whereas those of Phaeophyceae are in part extractible with hydrophobic solvents.Dumontia incrassata contains volatile compounds with a low antibiotic activity. The antibacterial properties ofDumontia incrassata are due to acidification of the culture medium by sulfuric acid, diffusing from the thalli into the agar.
Zusammenfassung
1. Die Aufarbeitungsmethoden zur Gewinnung antibakterieller Extrakte aus Meeresalgen werden im Hinblick auf Haltbarkeit und Trocknung des Materials untersucht.
2. Die antibakteriellen Eigenschaften der Präparate aus 9 Chlorophyceen, 16 Rhodophyceen und 16 Phaeophyceen gegen 4 gram-positive und 2 gram-negative Bakterienstämme werden bestimmt.
3. Die stärksten antibakteriellen Eigenschaften finden sich bei den Chlorophyceen. Von den Rhodophyceen haben nurChondrus crispus, Laurencia pinnatifida, Delesseria sanguinea und zum Teil auchRhodomela confervoides, von den PhaeophyceenHalidrys siliquosa, Fucus, Laminaria digitata undDesmarestia viridis eine deutliche Hemmwirkung.
4. Bei den Rhodophyceen und Chlorophyceen kommen überwiegend nur hydrophile, bei den Phaeophyceen auch mit lipophilen Lösungsmitteln extrahierbare Hemmstoffe vor.
5. BeiDumontia incrassata liegen leicht flüchtige, schwach wirksame Hemmstoffe vor; beiDesmarestia viridis geht die Antibiose auf eine Verschiebung des pH-Wertes des Kulturmediums durch die aus den Thalli hinausdiffundierende Schwefelsäure zurück.
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Glombitza, K.W. Antibakterielle Inhaltsstoffe in Algen. Helgolander Wiss. Meeresunters 19, 376–384 (1969). https://doi.org/10.1007/BF01611977
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DOI: https://doi.org/10.1007/BF01611977