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Table 1 Antibacterial activity of sea cucumber H. leucospilota extracts by disk diffusion method (inhibition zone, mm)

From: Antifouling and antibacterial activities of bioactive extracts from different organs of the sea cucumber Holothuria leucospilota

Microorganismn-Hexane extractsEthyl acetate extractsMethanol extractsAmpicillina
Body wallGonadDigestive tractRespiratory treeBody wallGonadDigestive tractRespiratory treeBody wallGonadDigestive tractRespiratory tree
S. aureus14.07 ± 0.30 cd13.83 ± 0.31de10.93 ± 0.35f8.83 ± 0.30 h16.37 ± 0.27a15.10 ± 0.22b13.70 ± 0.17e10.17 ± 0.13 g9.97 ± 0.21 g10.07 ± 0.13 g7.73 ± 0.21i_14.17 ± 0.13c
M. luteus10.23 ± 0.25b8.30 ± 0.24c7.50 ± 0.26e_11.97 ± 0.19a10.13 ± 0.30b8.40 ± 0.09c7.47 ± 0.05e8.03 ± 0.21d7.83 ± 0.13d__12.07 ± 0.13a
V. harveyi11.43 ± 0.30b11.47 ± 0.45b__12.40 ± 0.22a12.43 ± 0.17a7.47 ± 0.13d8.17 ± 0.13c8.03 ± 0.05c7.43 ± 0.10d7.07 ± 0.05e7.03 ± 0.05e11.37 ± 0.09b
E. coli9.97 ± 0.15c9.30 ± 0.24d__11.77 ± 0.26b9.90 ± 0.30c__8.00 ± 0.17e8.03 ± 0.05e__12.23 ± 0.20a
K. pneumoniae8.10 ± 0.17d8.10 ± 0.09d__9.53 ± 0.13b9.13 ± 0.13c__7.57 ± 0.13f___10.00 ± 0.33a
  1. Data are shown as the mean ± SD with different letters in the same row are significantly different at p < 0.05
  2. Inactive (–), weak active (< 7), moderately active (7–14); highly active (> 14)
  3. Inhibition zone includes diameter of the disc (6.4 mm)
  4. aTested at 10 µg/disc